Tamsulosin

DEA Class;  Rx

Common Brand Names; Flomax

Hypersensitivity

• Headache (19-21%)
• Orthostatic hypotension (6-19%)
• Rhinitis (13-18%)
• Abnormal ejaculation (8-18%)
• Dizziness (15-17%)
• Arthralgia (11%)
• Infection (9-11%)
• Asthenia (8%)
• Back pain (7-8%)
• Skin rash (7%)
• Pharyngitis (5-6%)
• Diarrhea (4-6%)
• Myalgia (5%)
• Chest pain (4%)
• Cough (3-4%)
• Somnolence (3-4%)
• Nausea (2-4%)
• Sinusitis (2-4%)
• Abdominal discomfort (2-3%)
• Bitter taste (2-3%)
• Decreased libido (1-2%)
• Insomnia (1-2%)

Use with caution in coronary artery disease, liver disease, general anesthesia

Orthostatic hypotension may occur

Priapism rarely reported

Prostatic cancer should be ruled out before therapy is initiated

May cause syncope (first-dose effect)

Discontinue if angina symptoms occur or worsen

Intraoperative floppy iris syndrome has been reported in patients receiving alpha1 blockers at time of cataract surgery; association is unclear

Patients with sulfa allergy have rarely developed allergic reaction; avoid use if previous sulfa allergy reactions have been life-threatening

Not for use as antihypertensive drug

May exacerbate heart failure

No data are available on use in pregnant women

No adverse developmental effects observed in animal studies administering tamsulosin to rats or rabbits during organogenesis

There are no data on presence of drug in human milk, effects on breastfed infant, or on milk production

No data are available; owing to potential of tamsulosin to cause hypotension, breastfeeding is not recommended if taking tamsulosin

Tamsulosin