Classes
DEA Class; Rx
Common Brand Names; Gramicidin, Neosporin Ophthalmic Solution, Neocin-PG
- Antibiotics, Ophthalmic Combos
Description
Aminoglycoside neomycin with polymyxin B and gramicidins A, B and C
Ophthalmic preparation; used for ophthalmic bacterial infections
Combination provides overlapping coverage against a wide range of gram-positive and gram-negative bacteria, including streptococci
Indications
Contraindications
Aminglycoside/neomycin hypersensitivity; hypersensitivity to any product component
Adverse Effects
Hypersensitivity
Itching, swelling, and conjunctival erythema
Local transient irritation
Vesicular and maculopapular dermatitis
Angioneurotic edema
Urticaria
Warnings
Watch for NEOMYCIN ocular sensitivity
Defects in visual acuity may occur with prolonged use
Posterior subpapular cataract formation, and secondary ocular infections reported with prolonged use
Prolonged use may result in overgrowth of nonsusceptible organisms including fungi; if superinfection occurs, appropriate measures should be initiated
Bacterial resistance to may develop; if purulent discharge, inflammation, or pain becomes aggravated, patient should discontinue use and consult a physician
Allergic cross-reactions may occur which could prevent use of any or all of the following antibiotics for treatment of future infections: kanamycin, paromomycin, streptomycin, and possibly gentamicin
Pregnancy and Lactation
Pregnancy
Animal reproduction studies have not been conducted with neomycin sulfate, polymyxin B sulfate, or bacitracin; not known whether therapy can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity; treatment should be given to a pregnant woman only if clearly needed
Lactation
Not known whether drug is excreted in human milk; because many drugs are excreted in human milk, exercise caution when drug is administered to a nursing woman
Maximum Dosage
Maximum dosage information not available.
Maximum dosage information not available.
Maximum dosage information not available.
Maximum dosage information not available; safety and efficacy have not been established.
Maximum dosage information not available; safety and efficacy have not been established.
How supplied
Neomycin/Polymyxin B/Gramicidin
ophthalmic solution
- (1.75 mg/10,000/0.025 mg)/1mL (10mL)
