Classes
DEA Class; Rx
Common Brand Names; Naftin
- Antifungals, Topical
Description
Topical allylamine antifungal
Indicated for the interdigital tinea pedis, tinea cruris, and tinea corporis
Similar efficacy and adverse events profiles to topical azole antifungals
Indications
Indications
- 1% cream: Indicated for treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organism Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum
- 1% gel: Indicated for treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organism Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton Tonsurans, and Epidermophyton floccosum
- 2% cream or gel: Indicated for treatment of interdigital tinea pedis, tinea cruris, and tinea corporis caused by the organism Trichophyton rubrum
Contraindications
Hypersensitivity
Adverse Effects
Transient burning/stinging (5-6%)
Skin tenderness (0.5-3%)
Dryness
Erythema
Pruritus
Local irritation
Rash
Warnings
Avoid use of occlusive dressings or wrappings
Keep the cream away from eyes, nose, mouth, & other mucous membranes
Reevaluate dx if no improvement after 4 wk
Discontinue treatment if irritation or sensitivity develops with use; direct patients to contact their physician if these conditions develop
Pregnancy and Lactation
Pregnancy: There are no available data in pregnant women to inform the drug-associated risk for major birth defects and miscarriage
Lactation: There is no information available on presence of drug in human milk, effects of drug on breastfed infant, or effects of drug on milk production
Maximum Dosage
No maximum dosage information is available.
No maximum dosage information is available.
No maximum dosage information is available for the 2% gel or 2% cream; safety and efficacy have not been established for all other formulations.
12 years: No maximum dosage information is available for the 2% gel or 2% cream; safety and efficacy have not been established for all other formulations.
2 to 11 years: No maximum dosage information is available for the 2% cream; safety and efficacy have not been established for all other formulations
< 2 years: Safety and efficacy have not been established.
Safety and efficacy have not been established.
Safety and efficacy have not been established.
How supplied
Naftifine hydrochloride
topical cream
- 1%
- 2%
topical gel
- 1%
- 2%