Classes
DEA Class; OTC
Common Brand Names; Doan’s Extra Strength, Percogesic Maximum Strength Backache Relief
- Salicylates
Description
NSAID with antipyretic and analgesic properties via central and peripheral effects
Indications
Indicated for Mild-to-Moderate Pain
Contraindications
Hypersensitivity
Advanced chronic renal impairment
Coadministration with uricosuric agents
Elderly patients (65 years or older) with carditis, hepatic impairment
Children and adolescents with viral illness (eg, varicella, influenza); increased risk for Reye’s syndrome
Warnings
Chronic ingestion of salicylates in patients older than 65 years may cause noncardiogenic pulmonary edema
May cause GI ulceration or bleeding
Consuming 3 or more alcoholic drinks daily may increase risk for GI bleeding
Caution in patients with asthma; may have increased risk for hypersensitivity or exacerbation of asthma
Do not take if on other chronic NSAIDs
Caution if coadministered with anticoagulant drugs
May cause tinnitus
Use caution in patients with dehydration, erosive gastritis or peptic ulcer
Heart Failure (HF) risk
Pregnancy and Lactation
Pregnancy Category: C
Lactation: Salicylates are excreted in breast milk; caution advised
Maximum Dosage
Mild-to-Moderate Pain
2 tabs PO q6hr PRN; not to exceed 8 tabs/24 hr
Pediatric
Mild-to-Moderate Pain
<12 years: Safety and efficacy not established
>12 years: 2 tabs PO q6hr PRN; not to exceed 8 tabs/24 hr
How supplied
Magnesium Salicylate
tablet
- 325 mg
- 580 mg as tetrahydrate (equal to 467.2 mg anhydrous magnesium salicylate)
- 600 mg
