Classes
DEA Class; OTC
Common Brand Names; Phillips’ M-O
- Laxatives, Lubricant
Description
Oral and rectal lubricant laxative, and topically as a skin protectant
Only laxative recommended for fecal impaction
Marketed prior to 1962, has not been evaluated formally by FDA for safety and efficacy.
Indications
Indicated for the relief of occasional constipation or fecal impaction.
Contraindications
Existing electrolyte imbalance, appendicitis symptoms, acute surgical abdomen, fecal impaction, intestinal obstruction or perforation, dysphagia, bedridden patients
Co-administration with stool softener
< 6 years
Hypersensitivity to drug or formulation components
Adverse Effects
- Hypotension
- Respiratory depression
- Lipid pneumonia if taken when reclined
- Excessive bowel activity
- Abdominal cramping
- Electrolyte imbalance
- Muscle weakness
- Anal pruritus and irritation
- Laxative dependence (Avoid chronic use)
Warnings
Renal insufficiency, Mg-restricted diet
If taken at bedtime, patient should not be reclining to avoid aspiration of oil droplets
Do not take within 2 hr of meals; may interfere with food nutrients & vitamins absorption
Use caution in patients with severe renal impairment
Pregnancy and Lactation
Pregnancy Category: C for mineral oil, B for magnesium hydroxide
Lactation: Use cautiously in breast feeding as it is unknown whether mineral oil is excreted into breast milk
Maximum Dosage
90 mL/day PO or 1 rectal enema/day PR for no longer than 1 week.
90 mL/day PO or 1 rectal enema/day PR for no longer than 1 week.
90 mL/day PO or 1 rectal enema/day PR for no longer than 1 week.
12 years: 90 mL/day PO or 1 rectal enema/day PR for no longer than 1 week.
6—11 years: 30 mL/day PO or 1/2 rectal enema/day PR for no longer than 1 week.
2—5 years: Oral safety and efficacy have not been established; 1/2 enema/day PR for no longer than 1 week.
< 2 years: Do not use.
Do not use.
Do not use.
How supplied
Magnesium hydroxide/mineral oil
oral solution
- (300 mg/1.25mL)/5mL
