Classes
DEA Class; OTC
Common Brand Names; Imodium Multi-Symptom Relief
- Antidiarrheals
Description
Antidiarrheal and antiflatulent combination product
Approved for self-treatment of acute diarrhea accompanied by bloating, cramps, and gas
Supratherapeutic doses of loperamide have been associated with serious, sometimes fatal, cardiac events
Indications
Indicated for self-treatment of acute diarrhea accompanied by bloating, cramps, pressure or flatulence.
Contraindications
Hypersensitivity, bloody diarrhea, high fever, infectious diarrhea, pseudomembranous colitis
Patients in whom constipation must be avoided
Abdominal pain without diarrhea
Avoid use as primary therapy with acute dysentery (bloody stools and high fever, acute ulcerative colitis, bacterial enterocolitis [caused by Salmonella, Shigella, and Campylobacter), pseudomembranous colitis associated with antibiotic use)
Age <2 years
Adverse Effects
- Dizziness
- Fatigue
- Headache
- Abdominal pain
- Dry mouth
- Nausea
- Diarrhea
- Vomiting
- Pancreatitis
Warnings
Chewable tab should be chewed thoroughly before swallowing
Pregnancy and Lactation
Pregnancy category: B (loperamide); C (simethicone)
Lactation: Unknown if distributed in to breast milk, use caution
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
Maximum Dosage
8 mg/24 hours PO loperamide; 500 mg/24 hours PO simethicone.
8 mg/24 hours PO loperamide; 500 mg/24 hours PO simethicone.
8 mg/24 hours PO loperamide; 500 mg/24 hours PO simethicone.
12 years: 8 mg/24 hours PO loperamide; 500 mg/24 hours PO simethicone.
9—11 years (60—95 pounds): 6 mg/24 hours PO loperamide; 375 mg/24 hours PO simethicone.
6—8 years (48—59 pounds): 4 mg/24 hours PO loperamide; 250 mg/24 hours PO simethicone.
< 6 years (<= 47 pounds): Safety and efficacy have not been established.
Safety and efficacy have not been established.
Safety and efficacy have not been established.
How supplied
Loperamide hydrochloride/simethicone
Imodium Multi-Symptom Relief/Loperamide Hydrochloride, Simethicone/Loperamide, Simethicone Oral Tab: 2-125mg
