Iodoquinol

DEA Class; Rx

Common Brand Names; Yodoxin

  • Antiparasitic Agents

Acts primarily in intestinal lumen; mechanism unknown

Indicated for Intestinal Amebiasis

Hypersensitivity to 8-hydroxyquinolones or iodoquinol

Iodine sensitivity

Pre-existing optic neuropathy

Hepatic damage

  • Headache
  • Chills
  • Agitation
  • Diarrhea
  • Rash
  • Fever
  • Urticaria
  • Pruritus
  • Thyroid gland enlargement
  • Retrograde amnesia
  • Nausea
  • Vomiting
  • Peripheral neuropathy
  • Optic neuritis
  • Stomach pain
  • Weakness
  • Visual impairment
  • Optic atrophy
  • Abdominal cramps
  • Itching of rectal area

Caution in thyroid disease

Interferes with thyroid tests for up to 6 months after discontiunation

Do not repeat course before 2-3 wk

Not effective in amebic hepatitis or liver abscess

Avoid long term thearpy (associated with optic neuritis and optic atrophy)

Pregnancy Category: C

Lactation: unknown

Adults

650 mg PO PC q8hr for 20 days; not to exceed 2 g/day

Pediatric

30-40 mg/kg/day divided PO PC q8hr PO for 20 days; not to exceed 1.95 g/day  

Geriatric

Not the drug of choice (may cause optic nerve damage); use only if other therapy is contraidicated or failed

Iodoquinol 

tablets

  • 210mg
  • 650mg

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