Gastrointestinal and Antiemetic Drugs (PPIs, Antacid, H2-Antihistaminic, Antidiarrheals, Laxatives, IBS, IBD)


Drugs Used to Treat Peptic Ulcer Disease.


ANTIMICROBIAL AGENTS

Amoxicillin Generic only
Bismuth compounds PEPTO-BISMOL, KAOPECTATE
Clarithromycin BIAXIN
Metronidazole FLAGYL
Tetracycline Generic only


H2-HISTAMINE RECEPTOR BLOCKERS

Cimetidine TAGAMET
Famotidine PEPCID
Nizatidine AXID
Ranitidine ZANTAC


PROTON PUMP INHIBITORS

Dexlansoprazole DEXILANT
Esomeprazole NEXIUM
Lansoprazole PREVACID
Omeprazole PRILOSEC
Pantoprazole PROTONIX
Rabeprazole ACIPHEX


PROSTAGLANDINS

Misoprostol CYTOTEC


ANTIMUSCARINIC AGENTS

Dicyclomine BENTYL


ANTACID

Aluminum hydroxide Generic only
Calcium carbonate TUMS
Magnesium hydroxide MILk OF MAGNESIA
Sodium bicarbonate ALKA-SELTZER


MUCOSAL PROTECTIVE AGENTS

Bismuth subsalicylate PEPTO-BISMOL
Sucralfate CARAFATE



Antiemetic drugs


PHENOTHIAZINES

Prochlorperazine Generic only


5-HT3 SEROTONIN RECEPTOR ANTAGONISTS

Dolasetron ANZEMET
Granisetron SANCUSO, SUSTOL
Ondansetron ZOFRAN
Palonosetron ALOXI


SUBSTITUTED BENZAMIDES

Metoclopramide REGLAN


BUTYROPHENONES

Droperidol Generic only
Haloperidol HALDOL


BENZODIAZEPINES

Alprazolam XANAX
Lorazepam ATIVAN


CORTICOSTEROIDS

Dexamethasone DECADRON
Methylprednisolone MEDROL


SUBSTANCE P/NEUROKININ-1 RECEPTOR ANTAGONIST

Aprepitant, Fosaprepitant EMEND
Netupitant* AKYNZEO
Rolapitant VARUBI



Antidiarrheals


ANTIMOTILITY AGENTS

Diphenoxylate + atropine LOMOTIL
Loperamide IMODIUM A-D


ADSORBENTS

Aluminum hydroxide Generic only
Methylcellulose CITRUCEL


AGENTS THAT MODIFY FLUID AND ELECTROLYTE TRANSPORT

Bismuth subsalicylate PEPTO-BISMOL



Laxatives


IRRITANTS and STIMULANTS

Bisacodyl CORRECTOL, DULCOLAX
Castor oil Generic only
Senna Ex-LAX, SENOKOT


BULK LAXATIVES

Methylcellulose CITRUCEL
Psyllium METAMUCIL


SALINE and OSMOTIC LAXATIVES

Lactulose CONSTULOSE, ENULOSE
Magnesium citrate CITROMA
Magnesium hydroxide MILk OF MAGNESIA
Polyethylene glycol GOLYTELY, MIRALAX


STOOL SOFTENERS

Docusate COLACE


LUBRICANT LAXATIVE

Glycerin suppositories Generic only
Mineral oil Generic only



Irritable Bowel Syndrome (IBS)


IBS-C AGENTS

Linaclotide LINZESS
Lubiprostone AMITIZA


IBS-D AGENTS

Alosetron LOTRONEX
Eluxadoline VIBEERZI
Rifaximin XIFAXAN


AGENTS FOR IBS-C AND IBS-D

Dicyclomine BENTYL
Hyoscyamine ANASPAZ, LEVBID, LEVSIN



DRUGS FOR IBD


5-AMINOSALICYCLATES

Oral Formulation

Balsalazide COLAZAL, GIAZO
Mesalamine ASACOL, PENTASA
Olsalazine DIPENTUM
Sulfasalazine AZULFIDINE

Rectal Formulation

Mesalamine enema ROWASA
Mesalamine suppository CANASA


CORTICOSTEROIDS

Oral Formulation

Budesonide delayed-release ENTOCORT EC
Budesonide extended-release UCERIS
Hydrocortisone CORTEF
Prednisone DELTASONE
Methylprednisolone MEDROL

Intravenous Formulation

Hydrocortisone SOLU-CORTEF
Methylprednisolone sOLU-MEDROL

Rectal Formulation

Budesonide foam UCERIS RECTAL
Hydrocortisone suppository ANUCORT-HC
Hydrocortisone enema CORTENEMA
Hydrocortisone foam CORTIFOAM


BIOLOGIC AGENTS

TNF-α Inhibitors

Adalimumab HUMIRA
Certolizumab CIMZIA
Golimumab SIMPONI
Infliximab REMICADE

α4-Integrin Inhibitors

Vedolizumab ENTYVIO

IL-12/23 Inhibitor

Ustekinumab STELARA


IMMUNOMODULATORS

Azathioprine IMURAN
6-Mercaptopurine Generic only
Methotrexate various

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