Classes
DEA Class; Rx
Common Brand Names; Terazol, Terazol 3, Terazol 7
- Antifungals, Vaginal
Description
Intravaginal azole antifungal
Used for vaginal candidiasis; usually fungicidal against Candida albicans
Indications
Indicated for Candidal Vulvovaginitis
Contraindications
Hypersensitivity
Adverse Effects
- Headache
- Abdominal pain
- Chills
- Fever
- Dysmenorrhea
- Vulvar/vaginal burning
- Dysmenorrhea
- Vulvar itching, soreness, edema, or discharge
- Polyuria
- Burning or itching of penis of sexual partner
- Flu-like syndrome
Warnings
Discontinue if irritation or sensitization occurs
Perform/repeat microbiological studies (KOH smear and/or cultures) in patients not responding to terconazole to rule out other pathogens
Anaphylaxis and toxic epidermal necrolysis (TENs) reported; discontinued if anaphylaxis or TENs develops
Product is petroleum-based, which may damage latex or rubber condoms or diaphragms (separate use by 3 days)
Discontinue use if toxic epidermal necrolysis occurs; institute supportive therapy and monitoring; do not reinstitute therapy
If flu-like symptoms or chills, fever occur, discontinue therapy and do not reinitiate
Pregnancy and Lactation
Pregnancy Category: C
Lactation: unknown
Maximum Dosage
1 applicatorful (20 or 40 mg terconazole/5 g cream) intravaginally/day; 1 suppository (80 mg terconazole) intravaginally/day.
1 applicatorful (20 or 40 mg terconazole/5 g cream) intravaginally/day; 1 suppository (80 mg terconazole) intravaginally/day.
Safety and efficacy have not been established; however, 1 applicatorful (20 or 40 mg terconazole/5 g cream) intravaginally/day and 1 suppository (80 mg terconazole) intravaginally/day have been used off-label.
Safety and efficacy have not been established.
Safety and efficacy have not been established.
Safety and efficacy have not been established.
How supplied
Terconazole
vaginal cream
- 0.4%
- 0.8%
suppository
- 80mg
