Classes
DEA Class; Rx
Common Brand Names; Pentostam, stibogluconate sodium
- Antileishmaniasis Agents
Description
Reduction in the fructose diphosphate and an inhibition of glycolysis
Indications
Indicated for the treatment of Leishmaniasis (Orphan)
Orphan designation for treatment of acute myeloid leukemia (AML)
Contraindications
Hypersensitivity
Significant renal impairment; breast-feeding
Adverse Effects
- Anorexia
- Nausea/vomiting
- Abdominal pain
- ECG changes
- Headache
- Lethargy
- Myalgia
- Raised liver enzymes
- Coughing and substernal pain
- Anaphylaxis (rare)
- Fever
- Sweating
- Flushing
- Vertigo
- Bleeding from nose or gum
- Jaundice
- Rash
- Pain and thrombosis on intravenous administration, intramuscular injection also painful
Pregnancy and Lactation
Pregnancy Category: unknown
Lactation: unknown
How supplied
Sodium stibogluconate
injectable solution
- 100mg Sb/mL
