Rimantadine

Brands

DEA Class; Rx

Common Brand Names; Flumadine

  • Antivirals, Influenza

Oral antiviral agent
Indicated for prophylaxis and treatment of seasonal influenza A virus infections in patients 17 years and older, and for prophylaxis only in children (1 to 16 years)
CDC and IDSA recommend against use due to high resistance

Indicated for the treatment of seasonal influenza A virus infection.

For seasonal influenza prophylaxis for infections due to influenza A virus.

Hypersensitivity to amantadine, rimantadine or any drug component

  • Dizziness (2%)
  • Nervousness (1-2%)
  • Fatigue (1%)
  • Headache (1%)
  • Insomnia (2%)
  • Difficulty in concentrating (<2%)
  • Anxiety (1%)
  • Anorexia (2%)
  • Weakness (1%)
  • Nausea (3%)
  • Vomiting (2%)
  • Xerostomia (2%)
  • Abdominal pain (1%)
  • Anorexia (2%)
  • Dyspnea
  • Agitation
  • Ataxia
  • Tachycardia
  • Tremor

CDC advises against use for treatment or prophylaxis of influenza in the US during the 2008-09 influenza season

Caution in patients with history of seizures; discontinue if seizures occur

Avoid use in patients with psychosis (active or uncontrolled)

Caution in renal impairment

Pregnancy Category: C

Lactation: enters breast milk

Adults

200 mg/day PO.

Geriatric

200 mg/day PO; 100 mg/day PO in elderly nursing home patients.

Adolescents

200 mg/day PO.

Children

10 to 12 years: 200 mg/day PO.
1 to 9 years: 5 mg/kg/day PO or 150 mg/day PO, whichever is less.

Infants

Safety and efficacy have not been established.

Neonates

Safety and efficacy have not been established.

Rimantadine

syrup

  • 50mg/5mL

tablet

  • 100mg
Drugs Generic
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