Classes
DEA Class; OTC
Common Brand Names; Enulose, Kristalose, Constulose, Generlac
- Laxatives, Osmotic;
- Ammonium Detoxicants
Description
Synthetic derivative of lactose; a disaccharide sugar containing one molecule of galactose and one molecule of fructose; used for hepatic encephalopathy and as a laxative.
Indications
Indicated for the treatment and prevention of hepatic encephalopathy.
Contraindications
Galactosemia (patients require low-galactose diet)
Adverse Effects
- Dehydration
- Diarrhea
- Excessive bowel activity
- Hypernatremia
- Hypokalemia
- Nausea
- Vomiting
- Abdominal cramping
- Abdominal distention
- Belching
- Flatulence
Warnings
Diabetes (preparation contains lactose and galactose)
Monitor for electrolyte imbalance when drug is used for >6 months or in patients predisposed to electrolyte abnormalities
Avoid using other laxatives concomitantly
Inadequate response possible when taken concomitantly with anti-infective
Pregnancy and Lactation
Pregnancy category: B
Lactation: Unknown whether drug is distributed into milk; use with caution
Maximum Dosage
Specific maximum dosage information is not available. Individualize dosage depending on route, indication, and frequency of bowel movements.
How supplied
Lactulose
oral/rectal solution
- 10g/15mL
packet
- 10g
- 20g
