Diethylpropion

DEA Class; Rx

Common Brand Names; 

• CNS Stimulants, Anorexiants; 
• Stimulants; 
• Sympathomimetic

Advanced arteriosclerosis

Hyperthyroidism

Severe hypertension

Pulmonary hypertension

Hypersensitivity to sympathomimetic amines

Glaucoma

Agitated state

History of drug abuse

Pregnancy (especially first trimester)

Within 14 days of MAOI

Concurrent use with other anorectic agents

• Increased blood pressure
• Palpitations
• Rash
• Urticaria
• Constipation
• Nausea
• Stomach cramps
• Vomiting
• Xerostomia
• Central nervous system stimulation
• Dizziness
• Headache
• Insomnia
• Pain
• Blurred vision
• Mydriasis
• Restlessness
• Menstrual irregularity
• Impotence, changes in libido

Therapy may impair ability of patient to engage in potentially hazardous activities such as operating machinery or driving motor vehicle; the patient should be cautioned accordingly

Prolonged use may induce dependence with withdrawal syndrome on cessation of therapy

Hallucinations have occurred rarely following high doses of the drug

Several cases of toxic psychosis reported following excessive use of drug; some have been reported in which recommended dose appears not to have been exceeded; new onset of mania may occur with stimulant use; ovserve for symptoms of aggression and/or hostility; psychosis has been abated after drug discontinued

When central nervous system active agents used, consideration must always be given to possibility of adverse interactions with alcohol

Reports suggest the drug may increase convulsions in some patients with seizure disorders; therapy should be carefully monitored; titration of dose or discontinuance of therapy may be necessary

Stimulants may unmask tics in Tourette’s syndrome; use with caution

Use caution in patients with diabetes mellitus; requirements of antidiabetic agents may be altered with anorexiants and concomitant dietary restrictions

Pregnancy Category: B

Lactation: Excreted in breast milk, use caution