Cromolyn Sodium

Brands

DEA Class; Rx

Common Brand Names; Gastrocrom, Crolom, NasalCrom

  • Mast Cell Stabilizers; 
  • Mast Cell Stabilizers, Ophthalmic

Mast-cell stabilizer; used in adult and pediatric patients 2 years and older
Nasal spray is used for allergic rhinitis; ophthalmic solution used for allergic conjunctivitis; used orall for systemic mastocytosis
Nebulizer solution used for asthma control or exercise-induced bronchospasm, but is not a preferred treatment

Indicated for use as an adjunct for asthma maintenance.

For exercise-induced bronchospasm prophylaxis or the prevention of bronchospasm induced by other known precipitating factors.
For the management of symptoms of seasonal allergies and perennial allergies, including allergic rhinitis and allergic rhinitis prophylaxis.
For the treatment of allergic ocular disorders such as allergic conjunctivitis, vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis.
For the treatment of systemic mastocytosis.

Hypersensitivity

Diarrhea

Headache

Angioedema

Premature ventricular contractions

Hypoesthesia

Lightheadedness

Flushing

Palpitation

Erythema

Postprandial

Photosensitivity

Behavior changes

Psychosis

Esophagospasm

Nausea

Abdominal pain

Pancytopenia

Polycythemia

Stomatitis

Neutropenia

Rash

Pruritus

Severe anaphylactic reactions may occur (rare)

Excreted through biliary and renal routes; monitor closely patients with hepatic/renal insufficiency; decrease dose in patients with impaired renal or hepatic function

Use caution in patients with history of cardiac arrhythmia and hepatic or renal impairment

Oral concentrated solution should not be used for inhalation or injection

Not beneficial in the acute setting

Symptoms may reoccur when tapering or withdrawing the drug; use caution

Pregnancy Category: B

Lactation: Unknown if excreted in breast milk, use caution

Adults

40 mg/kg/day PO; 20 mg inhaled via nebulization 4 times per day.

Geriatric

40 mg/kg/day PO; 20 mg inhaled via nebulization 4 times per day.

Adolescents

40 mg/kg/day PO; 20 mg inhaled via nebulization 4 times per day.

Children

2 to 12 years: 40 mg/kg/day PO; 20 mg inhaled via nebulization 4 times per day.
1 year: Safety and efficacy have not been established; 40 mg/kg/day PO is suggested. Safety and efficacy of other routes have not been established.

Infants

6 to 11 months: Safety and efficacy have not been established; 40 mg/kg/day PO is suggested. Safety and efficacy of other routes have not been established.
1 to 5 months: Safety and efficacy have not been established; 20 mg/kg/day PO is suggested. Safety and efficacy of other routes have not been established.

Neonates

Safety and efficacy have not been established.

Cromolyn sodium

oral concentrate

  • 100mg/5mL

ophthalmic solution

  • 4% (10mL)

nebulization solution

  • 10mg/mL (2mL/vial)

intranasal spray

  • 5.2mg/spray
Drugs Generic
Tags

About the Author

postblaze

You may also like these

0