Atenolol

DEA Class;  Rx

Common Brand Names; Tenormin

• Fatigue (13%)
• Hypotension (10%)
• Bradycardia (8%)
• Cold extremities (0.5- 7%)
• Postural hypotension (2-4%)
• Depression (3%)
• Nausea (2-3%)
• Dreaming (2%)
• Drowsiness (2%)
• Diarrhea (1-2%)
• Fatigue (1-2%)
• Leg pain (1-2%)
• Lethargy (1-2%)
• Lightheadedness (1-2%)
• Vertigo (1-2%)
• Dyspnea (0.4-2%)
• 2°/3° atrioventricular (AV) block (1%)

Use with caution in anesthesia or surgery (myocardial depression), bronchospastic disease, cerebrovascular insufficiency, diabetes mellitus, hyperthyroidism or thyrotoxicosis, liver disease, renal impairment, peripheral vascular disease, compromised left ventricular function, advanced age, heart failure

May mask effects of hyperthyroidism

Risk of hypoglycemia and bradycardia in neonates born to mothers who receive the drug at parturition or while breastfeeding, especially in premature infants and those with renal impairment

Use with caution in patients taking calcium-channel blockers or cardiac glycosides or using inhaled anesthetics

Avoid abrupt withdrawal; sudden discontinuance can exacerbate angina and lead to MI

Increased risk of stroke after surgery

In patients receiving clonidine, atenolol should be discontinued several days before withdrawal of clonidine

May cause or exacerbate CNS depression (use with caution in patients with psychiatric illness)

Pregnancy category: D

Lactation: Drug enters breast milk; neonates born to mothers who are receiving atenolol at parturition or breastfeeding may be at risk for hypoglycemia and bradycardia; use with caution

Atenolol