Diphenhydramine/Allantoin

DEA Class; OTC, Rx

Common Brand Names; Allegra Anti-Itch Cooling Relief Cream, Allegra Anti-Itch Intensive Relief Cream

  • Anesthetics, Topical; 
  • Dermatologics, Other

Diphenhydramine: Histamine H1-receptor antagonist; elicits topical anesthetic effects

Allantoin: Skin protectant

Temporarily relieves pain and itching associated with insect bites, minor skin irritations, sunburn, rashes, or minor burns, cuts, or scrapes

Hypersensitivity

Do not use more than directed

Do not use large areas of the body

Do not use with other diphenhydramine products, including oral products

Do not use on deep or puncture wounds, animal bites, or serious burns

Do not use on serious sunburn or broken, blistered or oozing skin

Advise patient to contact physician if condition worsens or symptoms persist beyond 7 days

Pregnancy Category: C

Lactation: Unknown whether distributed in breast milk

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

Apply to affected area PRN; not to exceed 3-4 applications/day

Diphenhydramine/allantoin

topical cream

  • 2%/0.5%

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