Classes
DEA Class; Rx
Common Brand Names; Brovex PB, Respahist-II, Vazotab Chewable, Children’s Dimetapp Cold & Allergy
- Antihistamine/Decongestant Combos
Description
Oral combination of an antihistamine and nasal decongestant
Used for the temporary relief of symptoms due to allergic rhinitis or other respiratory allergies or the common cold
May cause increased blood pressure and/or sedation; excitability may occur, especially in children
Indications
Indicated for the temporary relief of symptoms due to seasonal allergic rhinitis or the common cold, including sneezing, rhinorrhea, itching of the nose and throat, nasal congestion, and itchy, watery eyes.
Contraindications
Hypersensitivity to brompheniramine or phenylephrine
Use within 14 days of MAO therapy
Sedation of children
Breast feeding of newborn
Severe CAD or hypertension
Acute asthma attack
Urinary retention
Peptic ulcer
Adverse Effects
Phenylephrine (Common)
- Hypertension, reflex bradycardia
- Anxiety, dizziness, excitability, headache, nervousness, restlessness
- Rebound congestion, sneezing, pulmonary edema
- Brompheniramine (Common)
Anticholinergic effects (blurred vision, dry mouth/nose, throat)
- Drowsiness, dizziness, decreased coordination, headache
- Constipation, stomach upset
Warnings
May impair mental abilities (CNS depression)
Caution on CAD, diabetes mellitus, BPH, pyloroduodenal obstruction, respiratory disease, thyroid dysfunction
Pregnancy and Lactation
Pregnancy category: C; not recommended in first tri-mester or last 2 weeks of pregnancy
Lactation: Contraindicated
Maximum Dosage
24 mg/day PO brompheniramine and 60 mg/day PO phenylephrine.
24 mg/day PO brompheniramine and 60 mg/day PO phenylephrine.
24 mg/day PO brompheniramine and 60 mg/day PO phenylephrine.
12 years: 24 mg/day PO brompheniramine and 60 mg/day PO phenylephrine.
6 to 11 years: 12 mg/day PO brompheniramine and 30 mg/day PO phenylephrine.
1 to 5 years: Safety and efficacy have not been established.
Safety and efficacy have not been established.
Safety and efficacy have not been established.
How supplied
Brompheniramine/phenylephrine
tablet, chewable
- 6mg/15mg
oral suspension
- (6mg/10mg)/5mL
- (1.2mg/2mg)/1mL
oral liquid
- (1mg/2.5mg)/5mL
- (2mg/5mg)/5mL
elixir
- (1mg/2.5mg)/5mL
