Classes
DEA Class; OTC
Common Brand Names; PeriColace, Senna Plus, Senna-S, Senokot-S
- Laxatives, Stimulant
Description
Senna: intestinal irritant/stimulant
Docusate: surfactant laxative/stool softener
Indications
Indicated for treatment of Constipation
Contraindications
Hypersensitivity
GI obstruction or perforation
Ulcerative colitis
Symptoms of appendicitis or acute surgical abdomen
Fecal impaction
Concurrent use of mineral oil
GI bleeding
Rectal bleeding
Adverse Effects
- Abdominal cramping
- Diarrhea
- Nausea/vomiting
- Yellow-brown urine discoloration
Warnings
Finger clubbing (long-term use)
Not for use as over the counter in patients experiencing abdominal pain, vomiting, nausea, sudden change in bowel movement that last > 2 weeks
Not recommended for use >1 week or children < 2 years
Pregnancy and Lactation
Pregnancy category: C (senna); B psyllium
Lactation: Use caution
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
Maximum Dosage
Constipation
2-4 tablets PO qDay; may increase to 4 tab q12hr
How supplied
Senna/docusate
tablet
- 8.6mg/50mg
