Classes
Triamcinolone acetonide injectable suspension/nystatin
DEA Class; Rx
Common Brand Names; MyCo-Triacet II, Mycolog II, Mycogen II, Mytrex, Tri-Statin II
- Antifungal/Corticosteroid Topicals
Description
Nystatin and triamcinolone are used together topically for short-term (< 2 weeks) treatment of candidal skin infections. Nystatin is an antifungal agent and triamcinolone is a corticosteroid used for its antiinflammatory, vasoconstrictive, and antipruritic properties. Compared to nystatin or triamcinolone alone, the combination has been shown to provide faster and more pronounced clearing of erythema and pruritus, especially in the first few days of treatment.
Indications
Indicated for the short-term (i.e., less than 2 weeks) treatment of inflammatory cutaneous candidiasis caused by Candida albicans and other Candida sp..
Contraindications
Hypersensitivity
Adverse Effects
- Blistering
- Burning
- Dryness
- Acniform eruptions
- Excessive discoloring of the skin
- Excessive hair growth (especially on face)
- Hair loss (especially on scalp)
- Inflammation around the mouth
- Inflammation of hair follicles
- Irritation
- Itching
- Peeling
- Prickly heat
- Striae
- Secondary infection
- Skin inflammation
- Softening of the skin
- Stretch marks
- Stretching or thinning of the skin
Warnings
For topical use only
Not for ophthalmic use
Avoid contact with eyes
Patient should report any signs of adverse reactions
Systemic absorption of topical corticosteroids has produced reversible hypothalmic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria in some patients
Conditions that augment systemic absorption include application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings
Patients receiving a large dose of any potent topical steroid applied to a large surface area should be evaluated periodically for evidence of HPA axis suppression by using urinary free cortisol and ACTH stimulation tests, and for impairment of thermal homeostasis; if HPA axis suppression or elevation of body temperature occurs, make attempt to withdraw drug, reduce frequency of application, or substitute for less potent steroid
Recovery of HPA axis function and thermal homeostasis are generally prompt and complete upon discontinuation of drug; infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids
Children may absorb proportionally larger amounts of topical corticosteroids and thus may be more susceptible to systemic toxicity
If irritation or hypersensitivity develops with combination of nystatin and triamcinolone acetonide, discontinue treatment and institute appropriate therapy
Pregnancy and Lactation
Pregnancy Category: unknown
Lactation: unknown if excreted in breast milk
Maximum Dosage
No maximum dosage information is available.
No maximum dosage information is available.
No maximum dosage information is available.
No maximum dosage information is available.
How supplied
Triamcinolone/nystatin
topical cream/ointment
- (0.1%/100,000units)/g
