Acetyltributyl Citrate

Synonyms
Acetylbutyl citrate; acetylcitric acid, tributyl ester; ATBC; Citroflex A-4; tributyl acetylcitrate; tributylis acetylcitras; tributyl Oacetylcitrate; tributyl citrate acetate.

Description
Acetyltributyl citrate is a clear, odorless, practically colorless, oily liquid.

Chemical Name:   1,2,3-Propanetricarboxylic acid, 2-acetyloxy, tributyl ester 

  • Acetyltributyl citrate is used to plasticize polymers in formulated pharmaceutical coatings, including capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release and enteric formulations.

Acetyltributyl citrate is incompatible with strong alkalis and oxidizing materials.

Acetyltributyl citrate is used in oral pharmaceutical formulations and films intended for direct food contact. It is also used in selfadhesive thin films used for topical delivery systems. It is generally regarded as a relatively nontoxic and nonirritating material. However, ingestion of large quantities may be harmful.

Observe normal precautions appropriate to the circumstances and quantity of material handled. Acetyltributyl citrate is slightly irritating to the eyes and may be irritating to the respiratory system as a mist or at elevated temperatures. Gloves and eye protection are recommended for normal handling.

Acetyltriethyl citrate; tributyl citrate; triethyl citrate.

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